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Longevity Research Wiki

A hierarchical knowledge base for aging biology, longevity research, and cellular mechanisms.

Core Concepts

Theoretical frameworks for understanding aging:

Theories

Evolutionary frameworks for understanding aging:

Biological Mechanisms

Key cellular and molecular processes:

Model Organisms

Cancer Lineages

  • CTVT - 11,000-year-old dog cancer
  • DFTD - Tasmanian Devil Facial Tumor
  • HeLa - Henrietta Lacks immortal cells

Research Models

Comparative Biology

Animal Models

Research organisms used in longevity studies:

Proteins of Interest

Key molecular players in aging and longevity:

Research Areas

Key Papers

Essential research publications:

Key Researchers

Profiles of major contributors to longevity research.

Biochemical Pathways

Core signaling networks:

  • Insulin/IGF-1 - Growth signaling and longevity
  • mTOR - Mechanistic target of rapamycin
  • Autophagy - Cellular recycling and maintenance

This wiki extracts and organizes concepts from "The Price of Not Being Cancer" and other longevity research.